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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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[b]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors

Christian Lechner1,2, Maren Flaßhoff1, Hannes Falke1

  • 1Institut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Beethovenstraße 55, 38106 Braunschweig, Germany.

Molecules (Basel, Switzerland)
|November 27, 2019
PubMed

Keywords:
DYRK1AX-ray structure analysisindolemolecular dockingnephelometryprotein kinase inhibitorsolubility

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