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Methanol intoxication. Parkinsonism and decreased Met-enkephalin levels due to putaminal necrosis
W Verslegers1, M Van den Kerchove, R Crols
1Department of Neurology, Algemeen Ziekenhuis Middelheim, Antwerp, Belgium.
Acta Neurologica Belgica
|May 1, 1988
Abstract:
Due to methanol intoxication, a 38-year-old male developed permanent parkinsonism with visual impairment. Brain computerized tomography (CT) and magnetic resonance imaging (MRI) revealed cystic resorption of the putamen. An alteration of the central noradrenergic activity and the opioid system can be assumed because of increased dopamine beta-hydroxylase (D beta H) activity and decreased methionine-enkephalin (Met-Enk) levels in the cerebrospinal fluid (CSF).