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High-dose buprenorphine for treatment of high potency opioid use disorder
Marlon Danilewitz1,2, Mark McLean1,3
1British Columbia Centre on Substance Use, St. Paul's Hospital, Vancouver, Canada.
Abstract:
A 29-year-old woman presented to detox for treatment of an opioid use disorder with illicit fentanyl. While in detox, she was started on opioid agonist treatment with buprenorphine/naloxone. Unfortunately, she continued to have withdrawal symptoms despite being optimised to a dose of 32 mg. She was given additional PRNs of buprenorphine/naloxone to a total daily dose of 40 mg, which helped to alleviate her symptoms of withdrawal and cravings. She was stabilised on buprenorphine/naloxone 40 mg daily without any side effects and was discharged to a rehabilitation centre.
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