Aldehyde-mediated bioconjugation via in situ generated ylides

Sangeeta Parmar1, Sharad P Pawar1, Ramkumar Iyer1

  • 1Department of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal, Bhauri, Bhopal Bypass Road, Bhopal 462066, Madhya Pradesh, India. dimpy@iiserb.ac.in.

Chemical Communications (Cambridge, England)
|November 27, 2019
PubMed
Summary

A new bioconjugation method uses Wittig reactions for rapid, site-selective labeling of biomolecules. This simple technique works efficiently in vitro and within cells.

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