Related Experiment Video
Updated: Jan 3, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
[Optimizing the management of bladder cancer in older patients]
Y Neuzillet1, R Geiss2, E Paillaud2
1Service d'urologie et de transplantation rénale, hôpital Foch, université de Versailles-Saint-Quentin-en-Yvelines, 40, rue Worth, 92150 Suresnes, France.
Aim:
To define and present potential improvements for the management of bladder cancer in older patients.
Method:
Bibliographical search was performed from the Medline bibliographic database (NLM Pubmed tool) and Embase focused on: bladder cancer, treatment, BCG, chemotherapy, cystectomy, and elderly.
Results:
The oncological principles of medico-surgical management of bladder cancer do not differ according to age. On the other hand, the patient comorbidities have been likely to alter the tolerance of these treatments. At the NMIBC stages, no adaptation of the standard treatment has demonstrated any interest. At the MIBC stages, the prognosis was improved by geriatric multidisciplinary perioperative management.
Conclusion:
The indications and principles of surgical treatments must be identical regardless of the patient age. At the NMIBC stages, adjuvant therapy, including BCG therapy, should not be questioned because of the age of the patient. On the other hand, at the localized MIBC stages, neoadjuvant and adjuvant chemotherapy should not be considered as a standard and their indications assessed individually after geriatric assessment.
More Related Videos
Related Concept Videos
Urinary Tract Infection IV: Nursing Management
Urinary Tract Calculi III: Medical Management
Urinary Tract Calculi V: Nursing Management
Urinary Tract Calculi VI: Surgical Management
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

