Larval tick infestation causing an eruption of pruritic papules and pustules

Ticks are well-documented human parasites and vectors of infectious disease. The larval ("seed") stage is 1 of 3 motile life stages, and larval ticks have been known to attack in droves, causing diffuse pruritic erythematous papules and pustules. In the absence of close examination, larval tick infestation can easily be missed in the wide differential for this clinical presentation. We present 2 cases of larval tick infestation occurring during the summer within the same month at a single institution. Our purpose is to encourage physicians to include larval tick infestation when generating a differential diagnosis for diffuse pruritic erythematous papules and pustules.