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Covalently assembled dopamine nanoparticle as an intrinsic photosensitizer and pH-responsive nanocarrier for
Hong Li1, Yuanyuan Zhao1, Yi Jia2
1College of Chemistry and Chemical Engineering, Xi'an Shiyou University, Xi'an 710065, China.
Abstract:
We report a novel nanophotosensitizer via one-step covalent assembly of dopamine and genipin. This is the first report unveiling the photodynamic effect of dopamine-based materials. These nanophotosensitizers can also act as pH-responsive drug nanocarriers via a catechol-boronate linkage, thus achieving combined PDT and chemotherapy for highly efficient cancer treatment.

