Advanced primary urethral cancer: a case report
Huan Chen1, Li Li Zou2, Chuan Jiang Dong1
1Yichang Central People's Hospital, Institute of Urology, The First College of Clinical Medical Science, Three Gorges University, No. 183, Xiling District, Yichang, 443000, Yichang Hubei Province, China.
Primary urethral cancer is rare, often leading to delayed diagnosis. A conservative approach of tumor resection and bladder chemotherapy proved feasible for an elderly patient, improving quality of life.
Area of Science:
- Urology
- Oncology
Background:
- Primary urethral cancer is a rare malignancy with non-specific symptoms, often causing diagnostic delays.
- Limited clinical experience and lack of definitive treatment guidelines contribute to varied prognostic outcomes.
Observation:
- An 88-year-old female presented with progressive difficulty in urination.
- Postoperative pathology confirmed high-grade urothelial carcinoma of the urethra with extensive necrosis.
Findings:
- The patient underwent primary tumor resection combined with intravesical hydroxycamptothecin chemotherapy.
- This conservative treatment approach was feasible, allowing the patient to be discharged in stable condition.
Implications:
- Conservative treatment, including tumor resection and bladder perfusion chemotherapy, offers a viable option for elderly patients with primary urethral cancer.
- Dissemination of such cases is crucial for optimizing diagnosis and treatment strategies for this rare cancer.
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