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Short-T2 MRI: Principles and recent advances
Markus Weiger1, Klaas P Pruessmann1
1Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland.
Abstract:
Among current modalities of biomedical and diagnostic imaging, MRI stands out by virtue of its versatile contrast obtained without ionizing radiation. However, in various cases, e.g., water protons in tissues such as bone, tendon, and lung, MRI performance is limited by the rapid decay of resonance signals associated with short transverse relaxation times T2 or T2*. Efforts to address this shortcoming have led to a variety of specialized short-T2 techniques. Recent progress in this field expands the choice of methods and prompts fresh considerations with regard to instrumentation, data acquisition, and signal processing. In this review, the current status of short-T2 MRI is surveyed. In an attempt to structure the growing range of techniques, the presentation highlights overarching concepts and basic methodological options. The most frequently used approaches are described in detail, including acquisition strategies, image reconstruction, hardware requirements, means of introducing contrast, sources of artifacts, limitations, and applications.
Insights
Magnetic Resonance Imaging (MRI) faces challenges with short T2/T2* signals in tissues like bone. This review surveys specialized short T2 MRI techniques to improve imaging performance and overcome these limitations.
Area of Science:
- Biomedical Imaging
- Medical Physics
- Radiology
Background:
- Magnetic Resonance Imaging (MRI) offers versatile contrast without ionizing radiation.
- Signal decay (short T2 or T2* relaxation times) limits MRI performance in tissues like bone, tendon, and lung.
- Specialized techniques have been developed to address these signal decay limitations.
Purpose of the Study:
- To review the current status of short T2 MRI techniques.
- To structure the growing range of methods by highlighting overarching concepts and methodological options.
- To provide a detailed description of frequently used approaches.
Main Methods:
- Survey of existing literature on short T2 MRI.
- Categorization of techniques based on overarching concepts and methodological options.
- Detailed description of acquisition strategies, image reconstruction, hardware, contrast mechanisms, artifacts, limitations, and applications.
Main Results:
- Recent progress has expanded the available methods for short T2 MRI.
- The review categorizes and details various approaches to short T2 MRI.
- Key aspects covered include instrumentation, data acquisition, signal processing, and contrast introduction.
Conclusions:
- Short T2 MRI techniques are crucial for overcoming signal decay limitations in specific tissues.
- The review provides a structured overview of current methods, aiding in the selection and application of appropriate techniques.
- Continued advancements in instrumentation, acquisition, and processing are essential for further progress in short T2 MRI.
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