Related Experiment Video
Updated: Jan 3, 2026

Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial
Published on: September 29, 2015
Easy Platelet-Rich Fibrin (Injectable/Topical) for Post-resurfacing and Microneedle Therapy
1Facial Plastic Surgery, Gentile Facial Plastic Surgery and Aesthetic Laser Center, 821 Kentwood Suite C, Youngstown, OH 44512, USA; Facial Plastic Surgery, Cleveland Clinic Akron General Hospital, Akron, OH, USA.
Abstract:
The process of obtaining blood biologics, including platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), can be complicated and expensive and is influenced by many vendors and proprietary techniques. The indications for PRP/PRF use remain controversial, and complicated or expensive modes of generating this biologic may lead to many facial plastic surgeons to pass on the use of these potentially useful agents. The lack of standardization of PRP procurement also has led to difficulties in assessing clinical efficacy and comparing study protocols.
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