Related Experiment Video
Updated: Jan 3, 2026
08:12
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
2.1K
Surgical results for prosthetic versus native valve endocarditis: A multicenter analysis
Carolyn Weber1, Georgi Petrov2, Maximilian Luehr3
1Department of Cardiothoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany.
The Journal of Thoracic and Cardiovascular Surgery
|November 30, 2019
Summary
Prosthetic valve endocarditis (PVE) outcomes are comparable to native valve endocarditis (NVE) after adjusting for comorbidities. This study suggests PVE should not contraindicate redo cardiac surgery.
Area of Science:
- Cardiology
- Infective Diseases
- Cardiac Surgery
Background:
- Prosthetic valve endocarditis (PVE) is often associated with poorer outcomes than native valve endocarditis (NVE).
- A large-scale evaluation is needed to compare outcomes and identify risk factors in patients with infective endocarditis.
Purpose of the Study:
- To evaluate the impact of NVE versus PVE on postoperative outcomes and long-term survival.
- To identify preoperative risk factors in a large cohort of patients with infective endocarditis.
Main Methods:
- Retrospective cohort study of 4300 patients undergoing valve surgery for NVE or PVE across 5 German Cardiac Surgery Centers.
- Analysis included univariable and multivariable risk stratification, Kaplan-Meier survival analysis, and Cox proportional hazards regression.
Main Results:
- Patients with PVE were older and had more comorbidities, including hypertension, diabetes, coronary artery disease, and acute kidney injury.
- Initial analysis showed decreased long-term survival for PVE compared to NVE.
- Multivariable adjustment revealed no significant difference in long-term survival between PVE and NVE groups.
Conclusions:
- Long-term survival is comparable between PVE and NVE after adjusting for preoperative comorbidities.
- Prosthetic valve endocarditis should not be considered a contraindication for redo cardiac surgery based on this evidence.
Related Concept Videos
01:18Endocarditis III: Medical Management
181
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
181
01:25Endocarditis I: Introduction
335
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
335
01:25Endocarditis II: Clinical Features of Infective Endocarditis
333
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
333
01:29Endocarditis IV: Nursing Management
277
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
277
01:26Mitral Stenosis III: Medical Management
203
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
203
01:25Mitral Regurgitation III: Medical Management
229
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
229