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Updated: Jan 2, 2026

A Rat Model of EcoHIV Brain Infection
Published on: January 21, 2021
The impact of HIV central nervous system persistence on pathogenesis
Bruce J Brew1,2,3, Stephanie L Barnes1
1Departments of Neurology and HIV Medicine, St. Vincent's Hospital, Darlinghurst, Sydney.
Abstract:
: The persistence of HIV in the central nervous system is somewhat controversial particularly in the context of HIV viral suppression from combined antiretroviral therapy. Further, its significance in relation to HIV pathogenesis in the context of HIV-associated neurocognitive disorders, systemic HIV pathogenesis, and eradication in general, but especially from the brain, are even more contentious. This review will discuss each of these aspects in detail, highlighting new data, particularly from recent conference presentations.
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