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Updated: Jan 2, 2026

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The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
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Nitro-Substituted Ruthenium(II) Complex: A New Strategy for a G-Quadruplex DNA Fluorescent Probe
Xue-Wen Liu1,2, Ning-Yi Liu1, Yuan-Qing Deng1
1College of Chemistry and Material Engineering , Hunan University of Arts and Science , Changde 415000 , P. R. China.
Inorganic Chemistry
|December 4, 2019
Abstract:
A new strategy for a G-quadruplex fluorescent probe based on a nitro-substituted ruthenium complex is described. G-quadruplex DNA can be distinguished from double- or single-strand DNA by the naked eye. This ability originates from variation of the degree of protection of the nitro group on the complex from water by G-quadruplex and other structure DNAs.

