Physical properties of a new synthetic oxygen carrier

PFC emulsions have shown considerable promise for a variety of clinical indications, but their utility has been limited by instability outside the frozen state, extended tissue residence time, and complement activation. A new formulation from Adamantech, INc. based on F-MA and egg yolk phospholipid shows significant improvement in each of these areas. The emulsion can be stored in the non-frozen state, has a tissue half-life of 8-9 days, has excellent rheological properties, and does not activate complement.