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Related Concept Videos

Primary Lymphoid Organs01:16

Primary Lymphoid Organs

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Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
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Secondary Lymphoid Organs01:15

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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
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Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

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Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
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Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

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Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

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Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

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Primary cardiac lymphoma.

Alicia Xue Fen Chia1, Zitong Zhao2, See Lim Lim3

  • 1Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore alicia.cxf@hotmail.com.

BMJ Case Reports
|December 5, 2019
PubMed
Summary
This summary is machine-generated.

Primary cardiac lymphoma (PCL) is a rare heart tumor. Early diagnosis via modern imaging and biopsy, followed by chemotherapy, can lead to remission, as shown in this case study.

Keywords:
cardiovascular medicineoncology

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Area of Science:

  • Cardiology
  • Oncology
  • Pathology

Background:

  • Primary cardiac lymphoma (PCL) is a rare malignancy affecting the heart or pericardium.
  • Literature indicates a poor median survival of approximately 7 months for PCL patients.

Observation:

  • A 63-year-old woman presented with dyspnea and superior vena cava obstruction symptoms.
  • Imaging revealed a large right atrial tumor causing obstructive features.

Findings:

  • Diagnosis was confirmed via trans-jugular venous biopsy of the right atrial mass under trans-oesophageal echocardiography guidance.
  • The patient received seven cycles of chemotherapy.

Implications:

  • This case highlights the importance of advanced imaging and biopsy techniques for early PCL diagnosis.
  • Successful chemotherapy resulted in a 20-month remission, suggesting improved outcomes are possible with timely intervention.