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Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
Published on: February 6, 2019
Structural Brain Alterations Associated With Alcoholism
Margaret J Rosenbloom1, Adolf Pfefferbaum1, Edith V Sullivan1
1Margaret J. Rosenbloom, M.A., is a health science specialist in the Psychiatry Service, Veterans Affairs Palo Alto Health Care System, Palo Alto, California, and in the Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California. Adolf Pfefferbaum, M.D., is chief of psychiatric research, Veterans Affairs Palo Alto Health Care System, and a professor in the Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California. Edith V. Sullivan, Ph.D., is an associate professor in the Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, and a health science specialist in the Psychiatry Service, Veterans Affairs Palo Alto Health Care System, Palo Alto, California.
Abstract:
Structural changes in the brains of chronic heavy drinkers that were first observed in pathological studies have been supported and expanded upon using computed tomography (CT) and magnetic resonance imaging (MRI) techniques. In general, the volume of brain tissue appears decreased in chronic drinkers, and this finding may be affected by a person's age, gender, and other factors. MRI studies also demonstrate some increase in brain tissue volume after a chronic drinker has been abstinent for a period of months. Whether this tissue increase can be linked with recovery of brain functioning remains unanswered.
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