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Organocatalyzed Synthesis of Functionalized Quinolines
Lian-Hua Li1, Zhi-Jie Niu1, Yong-Min Liang1
1State Key Laboratory of Applied Organic Chemistry, National Demonstration Center for Experimental Chemistry Education, School of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, P. R. China.
Abstract:
As one of the most widely investigated compound skeleton, quinolines possess important medicinal and biological activities. As such, a great number of literatures, including reviews, have reported various methodologies to construct quinolines. Recently, organocatalyzed reactions have attracted the attention of organic chemists due to its being "green" because the reactions avoid the use of toxic metals. In this review, various distinctive contributions are surveyed with specific emphasis on organocatalyzed reactions for quinoline core constructions.
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