Predictive value of ATRIA risk score for contrast-induced nephropathy after percutaneous coronary intervention for

Fatih Aksoy1, Ali Bagcı2

  • 1MD, Associate Professor From the Department of Cardiology, Suleyman Demirel University, Medical School, Isparta, Turkey.

Revista Da Associacao Medica Brasileira (1992)
|December 5, 2019
PubMed

Insights

The ATRIA and CHA2DS2-VASC risk scores can effectively predict contrast-induced nephropathy (CIN) in acute myocardial infarction (AMI) patients undergoing percutaneous coronary intervention (PCI). These scores demonstrate utility in identifying patients at risk for CIN post-STEMI.

Area of Science:

  • Cardiology
  • Nephrology
  • Clinical Risk Prediction

Background:

  • The AnTicoagulation and Risk factors In Atrial fibrillation (ATRIA) risk score, initially for atrial fibrillation (AF) patients, shows potential in predicting outcomes for acute myocardial infarction (ACS) patients.
  • Contrast-induced nephropathy (CIN) is a significant complication following percutaneous coronary intervention (PCI) in ACS patients.

Purpose of the Study:

  • To analyze the relationship between risk scores and CIN development in ACS patients undergoing urgent PCI.
  • To compare the predictive ability of the ATRIA risk score against the MEHRAN risk score for CIN.

Main Methods:

  • Analysis of 429 patients with ST-segment Elevation Myocardial Infarction (STEMI) undergoing urgent PCI.
  • Comparison of clinical, laboratory, and demographic features between patients with and without CIN, including ATRIA and CHA2DS2-VASc risk scores.
  • Multivariate regression and Receiver Operating Characteristic (ROC) curve analysis to determine predictors and prognostic value for CIN.

Main Results:

  • ATRIA risk score, Opaque/Creatinine Clearance ratio, and low left ventricular ejection fraction were independent predictors of CIN.
  • C-statistics for ATRIA and CHA2DS2-VASC scores were 0.66 and 0.64, respectively, indicating significant predictive value.
  • Both ATRIA and CHA2DS2-VASC scores were not inferior to the MEHRAN score in predicting CIN.

Conclusions:

  • The ATRIA and CHA2DS2-VASC scoring systems are valuable tools for identifying CIN risk in STEMI patients post-PCI.
  • These established risk scores offer a practical approach to CIN risk stratification in this patient population.
Abstract

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