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Adenovirus as a rare cause of acute necrotising encephalitis

Nida Sakrani1, Safaa Almazrouei2, Shyam Mohan3

  • 1Pediatrics, Shaikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.

BMJ Case Reports
|December 6, 2019
PubMed

Insights

Adenovirus can cause respiratory infections and rarely, severe neurological conditions like acute necrotising encephalopathy (ANE). This case report details a child with adenovirus-induced ANE, emphasizing early diagnosis for better outcomes.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Pediatrics

Background:

  • Adenovirus commonly causes respiratory infections.
  • Neurological complications, including acute necrotising encephalopathy (ANE), are rare but serious.
  • The pathogenesis of adenovirus-associated ANE remains poorly understood.

Observation:

  • This report details a case of a previously healthy 14-month-old girl.
  • The patient presented with symptoms indicative of ANE.
  • Diagnosis was confirmed as adenovirus-induced ANE.

Findings:

  • The case highlights the clinicoradiological manifestations of ANE secondary to adenovirus infection.
  • This uncommon association requires a high index of suspicion for timely identification.

Implications:

  • Early diagnosis of adenovirus-induced ANE is crucial for improving patient outcomes.
  • Further research into the pathogenesis may lead to targeted treatments.
  • This case underscores the importance of considering neurological complications in children with adenovirus infections.
Keywords:
infection (neurology)neuroimaging

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