Nanotechnology intervention of the microbiome for cancer therapy

Wantong Song1, Aaron C Anselmo2, Leaf Huang3,4

  • 1Key Laboratory of Polymer Ecomaterials, Jilin Biomedical Polymers Engineering Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, People's Republic of China.

Nature Nanotechnology
|December 6, 2019
PubMed

Insights

Nanotechnology offers innovative strategies for cancer treatment by targeting the microbiome. This review explores opportunities at the intersection of nanotechnology, the microbiome, and cancer therapy.

Area of Science:

  • Oncology
  • Microbiology
  • Nanotechnology

Background:

  • The microbiome significantly influences cancer development and progression.
  • Current microbiome manipulation methods (antibiotics, probiotics, transplants) have limitations like collateral damage and inconsistency.
  • There is a need for novel technologies specifically designed for the microbiome-cancer interface.

Purpose of the Study:

  • To highlight opportunistic areas for applying nanotechnologies to manipulate the microbiome for cancer treatment.
  • To provide an overview of seminal work in this emerging field.
  • To discuss future challenges and perspectives.

Main Methods:

  • Review of existing literature on nanotechnology, microbiome, and cancer.
  • Identification of key areas where nanotechnologies can interface with the microbiome and tumor microenvironment.
  • Analysis of the potential of nanotechnologies for cancer therapy.

Main Results:

  • Nanotechnologies present significant opportunities for innovative cancer treatment strategies.
  • Targeting the microbiome with nanotech can overcome limitations of traditional methods.
  • The intersection of nanotechnology, microbiome, and cancer offers vast potential.

Conclusions:

  • Nanotechnology holds immense promise for developing targeted cancer therapies by modulating the microbiome.
  • Further research and development are crucial to overcome challenges and realize the full potential of this interdisciplinary field.
  • This emerging area offers a paradigm shift in cancer treatment approaches.

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