[Current problems of arboviruses in central Africa]

19 arboviruses pathogenic for human are present in the Central African Republic (CAR) where serologic data indicate an active circulation in human population. In most cases the clinical picture of infection is mild. However 3 arbovirus were recently involved in fatal cases: in 1983 West-Nile virus has been isolated in 4 patients with hepatitis. 2 fatal cases of Yellow Fever occurred in 1985 and 1986, and from 1983 to 1986 Rift Valley Fever virus was isolated in patients who died from hemorrhagic fever. This new situation requires to carry on an epidemiological survey and studies on virus pathogenicity.