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Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface
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Red complex: Polymicrobial conglomerate in oral flora: A review
Rinkee Mohanty1, Swati Joshi Asopa2, M Derick Joseph3
1Department of Periodontics, Institute of Dental Sciences, SOA Deemed to University, Bhubaneswar, Odisha, India.
Journal of Family Medicine and Primary Care
|December 6, 2019
Summary
This review examines the virulence of the "red complex" bacteria, including P. gingivalis, T. denticola, and T. forsythia, which are linked to severe gum disease (periodontitis). Understanding these oral pathogens is key to combating destructive inflammatory responses.
Area of Science:
- Oral microbiology
- Periodontology
- Host-pathogen interactions
Background:
- Oral diseases involve complex inflammatory responses to microbial challenges.
- Periodontitis is characterized by progressive soft and hard tissue destruction.
- The
Purpose of the Study:
- To review the virulence factors of key bacteria implicated in periodontitis.
- To examine the pathogenic potential of the
Main Methods:
- Literature review of studies on oral pathogens.
- Analysis of bacterial virulence determinants.
- Examination of host response mechanisms.
Main Results:
- The
Conclusions:
- The
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