Related Experiment Video
Updated: Jan 2, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Preventing strokes in people with atrial fibrillation by improving ABC
Jagjot Kaur Chahal1, Sotiris Antoniou1,2, Mark Earley3
1Department of Pharmacy, Barts Health NHS Trust, London, UK.
Insights
A new program significantly improved anticoagulation rates in atrial fibrillation (AF) patients by 6.3%, outperforming national averages. This initiative also reduced inappropriate antiplatelet use and improved blood pressure and cholesterol management.
Area of Science:
- Cardiology
- Pharmacology
- Public Health
Background:
- Anticoagulation for atrial fibrillation (AF) shows significant provider variation nationally.
- Uncontrolled blood pressure and coronary artery disease exacerbate cardiovascular risk in AF patients.
- The ABC of AF improvement program aimed to address these management gaps.
Purpose of the Study:
- To implement and evaluate a program to enhance anticoagulation, blood pressure, and cholesterol management in AF patients.
- To reduce provider variation in AF care within the Redbridge Clinical Commissioning Group (CCG).
Main Methods:
- A clinical pharmacist utilized Active Patient Link (APL-AF) software across 43 general practices to identify eligible AF patients.
- Patients received GP-pharmacist consultations for anticoagulation initiation and optimization of blood pressure and lipid treatments.
- Multidisciplinary team (MDT) video conferences facilitated complex patient case discussions with specialists.
Main Results:
- Anticoagulation in eligible AF patients increased by 6.3% (77.0% to 83.3%), significantly exceeding the 2.8% national improvement.
- Exception reporting decreased by 4.2%, compared to a 1.5% national reduction.
- Use of antiplatelet monotherapy was reduced by approximately 50% (12.3% to 6.4%).
Conclusions:
- The ABC of AF program successfully improved anticoagulation rates and cardiovascular risk factor management in AF patients.
- The implemented methods demonstrated significant improvements over national averages and are suitable for wider scalability.
- This model offers a potential national strategy for improving care in lower-performing CCGs.
Abstract:
Nationally, anticoagulation for atrial fibrillation (AF) is improving but remains characterised by marked provider variation. Uncontrolled blood pressure and coronary artery disease further increase cardiovascular risk. Redbridge Clinical Commissioning Group (CCG) and local National Health Service (NHS) hospital trusts supported a programme to improve anticoagulation, blood pressure and cholesterol management; the ABC of AF improvement. The programme was delivered by a clinical pharmacist in 43 general practices, who used Active Patient Link (APL-AF) software to identify and electronically review the records of AF patients potentially suitable for anticoagulation. These patients were invited for a general practitioner (GP)-pharmacist consultation with initiation of anticoagulation where appropriate. Blood pressure and lipid treatment were also optimised. The university-based Clinical Effectiveness Group (CEG) provided software support using standard data entry templates from which the APL-AF software was enabled. This identified suitable patients (eg, on aspirin monotherapy, no treatment or inappropriate dual treatments) for clinical and treatment review. It also reported real-time overall practice performance. Additionally, GP education on direct oral anticoagulant initiation in general practices, use of software and performance reviews, took place for all practices in Redbridge. A weekly multidisciplinary team (MDT) video conference discussed complex patients with a cardiologist, haematologist, GP with specialist interest in cardiology, GP coordinator and clinical pharmacist. This enabled sharing of patient records between GPs and hospital specialists with improved communication and learning. Over 1 year 2016-2017, anticoagulation in eligible AF patients (CHA2DS2-VASc≥2) increased significantly by 6.3% from 77.0% to 83.3% (p<0.0001), in comparison to 2.8% average improvement in England. Exception reporting was also significantly reduced from 10.0% to 5.8%; a reduction of 4.2% in comparison to a reduction in England of 1.5%. Use of antiplatelet monotherapy was approximately halved, from 12.3% to 6.4%. These methods are being scaled locally in other London CCGs and are potentially scalable nationally, specifically targeting the poorer performing CCGs.
Related Concept Videos
Dysrhythmias VI: Management of Dysrhythmias
Atherosclerosis III: Management
Atherosclerosis IV: Nursing Management
Coronary Artery Disease IV: Preventive Measures
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Acute Coronary Syndrome IV: Interprofessional Care

