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Updated: Jan 2, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Use of a Transfusion Checklist by Student Nurses to Improve Patient Safety
Sue S Scott1, Elizabeth A Henneman, Brian H Nathanson
1Sue S. Scott, PhD, RN, is Assistant Professor in Nursing, Westfield State University, Massachusetts. Elizabeth A. Henneman, PhD, RN, is Professor, College or Nursing, University of Massachusetts, Amherst. Brian H. Nathanson, PhD, is Chief Executive Officer, OptiStaTim, LLC, Longmeadow, Massachusetts. Chester Andrzejewski Jr., MD, PhD, is Medical Director Baystate Health, Transfusion Medicine Services, Springfield, Massachusetts. Megan Gonzalez, MSN, RN, is Simulation Lab Coordinator, Westfield State University, Massachusetts. Rachel Walker, PhD, RN, is Assistant Professor in Nursing, University of Massachusetts, Amherst. Vanessa I. Martinez, MS, is with the Department of Mechanical and Industrial Engineering, University of Massachusetts, Amherst.
A checklist improved management behaviors for transfusion-associated adverse events in student nurses. However, overall recognition of these events did not significantly increase, suggesting checklists may enhance patient safety through improved identification behaviors.
Area of Science:
- Nursing Education
- Patient Safety
- Healthcare Quality Improvement
Background:
- Enhanced education is needed for recognizing transfusion-associated adverse events.
- The impact of checklist use on student nurses' recognition of these events is not well understood.
- Improving the identification of adverse events is crucial for patient safety.
Purpose of the Study:
- To investigate if a checklist improves transfusion-associated adverse event recognition behaviors in student nurses.
- To assess the effectiveness of checklists in enhancing the identification and management of adverse events during blood transfusions.
- To determine the potential of checklists in improving patient safety outcomes related to transfusion reactions.
Main Methods:
- A study was conducted involving student nurses to evaluate the use of a checklist.
- The study compared recognition and management behaviors related to transfusion-associated adverse events between groups.
- Data were collected to analyze the impact of checklist intervention on student nurse performance.
Main Results:
- The group using the checklist demonstrated an increased frequency of transfusion-associated adverse event management behaviors.
- Overall recognition of transfusion-associated adverse events was not significantly greater in the checklist group compared to control groups.
- Checklist use positively influenced the procedural management of identified adverse events.
Conclusions:
- A transfusion-associated adverse event checklist may enhance patient safety by promoting specific identification behaviors.
- While overall recognition did not improve, checklist use supports better management of adverse events.
- Further research is warranted to optimize checklist design and implementation for improved recognition.
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