Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

886
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
886
Vaccinations01:51

Vaccinations

51.0K
Overview
51.0K
Cancer Vaccines01:30

Cancer Vaccines

897
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
897
Cross-reactivity00:42

Cross-reactivity

32.7K
Overview
32.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protective human antibodies against Powassan virus.

Journal of virology·2026
Same author

CAR-T Targeting of Mutant Calreticulin Establishes a Potentially Curative Stem Cell-Directed Therapy for Myeloproliferative Neoplasms.

bioRxiv : the preprint server for biology·2026
Same author

Next-generation anti-DLL3 radiopharmaceuticals targeting high-grade neuroendocrine lung and prostate cancers.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

ROS-activatable Prodrug of Doxazolidine as Novel Cancer Therapy Paradigm.

Advanced therapeutics·2026
Same author

Dissecting the Unique Self-Assembly Landscape of the HIV-2 Capsid Protein.

Viruses·2025
Same author

Hantavirus Gn<sup>H</sup> Nanoparticle Immunogen Elicits a Cross-Neutralizing Antibody Response in Mice.

ACS infectious diseases·2025
Same journal

Conditional Transmembrane Peptides as Allosteric Modulators: Thermodynamic and Functional Perspectives in Membrane Protein Regulation.

Chemical reviews·2026
Same journal

Introduction to Semi-artificial Photosynthesis.

Chemical reviews·2026
Same journal

Synthetic Porous Carbons for High-Energy, High-Power Supercapacitors.

Chemical reviews·2026
Same journal

Navigating Misfolded Terrain: ER-Associated Degradation of Membrane Proteins.

Chemical reviews·2026
Same journal

Ink Design for Printing Perovskite Solar Cells and Modules.

Chemical reviews·2026
Same journal

Advanced Single-Atom Catalysts for Thermal-Catalytic C1 Chemistry.

Chemical reviews·2026
See all related articles

Related Experiment Video

Updated: Jan 2, 2026

Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo
07:33

Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo

Published on: September 28, 2022

2.1K

Peptide-Based Vaccines: Current Progress and Future Challenges.

Ryan J Malonis1, Jonathan R Lai1, Olivia Vergnolle1

  • 1Department of Biochemistry, Albert Einstein College of Medicine, Michael F. Price Center for Translational Research, 1301 Morris Park Avenue, Bronx, New York 10461, United States.

Chemical Reviews
|December 6, 2019
PubMed
Summary
This summary is machine-generated.

Peptide vaccines show promise for preventing infectious diseases, Alzheimer's disease, and cancer. Continued research is needed to overcome challenges and enable wider clinical use of these innovative vaccines.

More Related Videos

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction
10:18

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction

Published on: July 7, 2023

1.6K
Synthesis and Characterization of mRNA-Loaded PolyBeta Aminoesters Nanoparticles for Vaccination Purposes
08:27

Synthesis and Characterization of mRNA-Loaded PolyBeta Aminoesters Nanoparticles for Vaccination Purposes

Published on: August 13, 2021

4.9K

Related Experiment Videos

Last Updated: Jan 2, 2026

Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo
07:33

Preparation, Characteristics, Toxicity, and Efficacy Evaluation of the Nasal Self-Assembled Nanoemulsion Tumor Vaccine In Vitro and In Vivo

Published on: September 28, 2022

2.1K
Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction
10:18

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction

Published on: July 7, 2023

1.6K
Synthesis and Characterization of mRNA-Loaded PolyBeta Aminoesters Nanoparticles for Vaccination Purposes
08:27

Synthesis and Characterization of mRNA-Loaded PolyBeta Aminoesters Nanoparticles for Vaccination Purposes

Published on: August 13, 2021

4.9K

Area of Science:

  • Immunology
  • Vaccinology
  • Therapeutic Development

Background:

  • Vaccines are crucial for infectious disease control.
  • Developing vaccines for chronic diseases like cancer and Alzheimer's is a growing area of interest.
  • Subunit vaccines utilize specific disease components or epitopes.

Purpose of the Study:

  • To review peptide-based vaccines for infectious disease, Alzheimer's disease, and cancer.
  • To discuss factors influencing vaccine efficacy and design modulation.
  • To explore current and emerging peptide vaccine approaches, challenges, and solutions.

Main Methods:

  • Review of existing literature on peptide-based vaccines.
  • Analysis of clinically tested and novel vaccine strategies.
  • Examination of factors affecting vaccine performance and design.

Main Results:

  • Peptide vaccines offer potential for preventing multiple diseases.
  • Vaccine efficacy is influenced by specific design parameters.
  • Several challenges impede the clinical application of peptide vaccines.

Conclusions:

  • Peptide vaccines hold significant promise for human disease prevention.
  • Overcoming current obstacles is essential for clinical translation.
  • Further research is warranted to advance peptide vaccine technology.