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Endogenous opiates and behavior: 2017.

Richard J Bodnar1

  • 1Department of Psychology and Neuropsychology Doctoral Sub-Program, Queens College, City University of New York, CUNY, 65-30 Kissena Blvd., Flushing, NY, 11367, United States.

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|December 6, 2019
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Summary
This summary is machine-generated.

This review covers 2017 research on the endogenous opioid system, detailing how manipulating opioid peptides and receptors impacts behavior. It explores roles in pain, addiction, mood, and various physiological functions.

Keywords:
Delta opioid receptorDynorphinsEndomorphinsEndorphinsEnkephalinsKappa opioid receptorMu opioid receptorNociceptionOrphan opioid receptorTolerance and dependence

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Area of Science:

  • Neuroscience
  • Pharmacology
  • Behavioral Science

Background:

  • The endogenous opioid system modulates numerous physiological and behavioral processes.
  • Understanding its intricacies is crucial for therapeutic interventions.

Purpose of the Study:

  • To provide a comprehensive review of research published in 2017 on the endogenous opioid system.
  • To summarize findings on the behavioral effects of manipulating opioid peptides and receptors.

Main Methods:

  • Anthological review of scientific literature published in 2017.
  • Categorization of studies based on molecular, pharmacological, and genetic manipulations.
  • Analysis of behavioral outcomes related to opioid agonists and antagonists.

Main Results:

  • Extensive research in 2017 explored opioid system roles in pain, analgesia, tolerance, dependence, stress, learning, and mood.
  • Studies investigated opioid involvement in eating, drug abuse, sexual activity, and neurological disorders.
  • The review covers effects on cardiovascular, respiratory, gastrointestinal, and immunological functions.

Conclusions:

  • The endogenous opioid system remains a critical area of research with broad implications.
  • Continued investigation is vital for understanding and treating a wide range of conditions.