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Simultaneous Assessment of Left Ventricular Function and Coronary Artery Anatomy by Third-generation Dual-source
Ji Won Lee1, Kyung Jin Nam2, Jin You Kim1
1Department of Radiology, Pusan National University School of Medicine and Medical Research Institute, Pusan National University Hospital, Busan, Korea.
Insights
Third-generation dual-source CT effectively assesses left ventricular function and coronary artery disease simultaneously. This low-radiation dose imaging provides valuable diagnostic information, serving as a potential alternative to other modalities.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Assessing left ventricular (LV) function and coronary artery disease (CAD) is crucial in cardiovascular diagnostics.
- Traditional methods may require multiple imaging modalities, increasing patient burden and radiation exposure.
- Third-generation dual-source computed tomography (CT) offers potential for simultaneous assessment.
Purpose of the Study:
- To evaluate the efficacy of third-generation dual-source CT in simultaneously assessing LV function and coronary arteries.
- To determine the diagnostic accuracy and radiation dose of this low-tube-voltage CT technique.
Main Methods:
- A retrospective study included 48 patients who underwent electrocardiography-gated cardiac CT angiography (CCTA) with 70-90 kVp and echocardiography.
- LV volumes (LVEDV, LVESV) and ejection fraction (LVEF) were compared between CCTA and echocardiography.
- Coronary artery image quality was assessed using a 4-point scale, and effective radiation dose was calculated.
Main Results:
- CCTA showed fair to moderate correlation with echocardiography for LVEDV (r=0.395), LVESV (r=0.509), and LVEF (r=0.551).
- Excellent image quality (score 1.0 ± 0.1) was achieved for 99% of coronary artery segments.
- The mean effective radiation dose was low, averaging 2.2 ± 0.7 mSv.
Conclusions:
- Third-generation dual-source CT with low tube voltage enables simultaneous assessment of LV function and coronary arteries at a low radiation dose.
- This technique provides valuable diagnostic information and can be a viable alternative when other imaging modalities are insufficient.
Background:
To assess left ventricular function and coronary artery simultaneously by third-generation dual-source computed tomography (CT) using a low radiation dose.
Methods:
A total of 48 patients (36 men, 12 women; mean age 57.0 ± 9.5 years) who underwent both electrocardiography-gated cardiac CT angiography (CCTA) using 70-90 kVp and echocardiography were included in this retrospective study. The correlation between left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), and left ventricular ejection fraction (LVEF) measured using CCTA and echocardiography was determined. The quality of coronary artery images was analyzed using a 4-point scale (1, excellent; 4, poor). The effective radiation dose of CCTA was calculated.
Results:
Mean heart rate during the CT examination was 59.9 ± 9.9 bpm (range 38-79) and the body mass index of 48 patients was 24.5 ± 2.6 kg/m² (range 17.0-29.4). LVEDV, LVESV, and LVEF measured using CCTA and echocardiography demonstrated a fair to moderate correlation (Pearson correlation coefficient: r = 0.395, p = 0.005 for LVEDV; r = 0.509. p < 0.001 for LVESV; r = 0.551, p < 0.001 for LVEF). Average image quality score of coronary arteries was 1.0 ± 0.1 (range 1-2). A total of 99.0% (783 of 791) of segments had an excellent image quality score, and 1.0% (8 of 791) of segments had a good score. Mean effective radiation dose was 2.2 ± 0.7 mSv.
Conclusions:
Third-generation dual-source CT using a low tube voltage simultaneously provides information regarding LV function and coronary artery disease at a low radiation dose. It can serve as an alternative option for functional assessment, particularly when other imaging modalities are inadequate.
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