Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Assembly of the Lipid Bilayer in the ER

Assembly of the Lipid Bilayer in the ER

Biological membranes are more than just a barrier separating cell cytoplasm from the outside environment. They are highly dynamic and help maintain the integrity and physiological stability of the cells as well as membrane-bound organelles. Membranes also play vital roles in cell-to-cell and intracellular communication.
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...

Asymmetric Lipid Bilayer

Asymmetric Lipid Bilayer

Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Somatic variant-calling beyond cancer: Repurposing algorithms to map low‑allele‑fraction variants across genomics.

Mutation research. Reviews in mutation research·2026

Same author

The effect of polyallergy on ancillary service use among postoperative patients with gynecologic malignancies.

Gynecologic oncology reports·2026

Same author

Evaluating the immediate impacts of the repeal of the Northern Territory minimum unit price on off-premises alcohol pricing: Findings from an observational study of online alcohol retailers.

Addiction (Abingdon, England)·2026

Same author

Asymmetrical Two-Headed Linear Cationic Surfactants with Halogenoferrate Magnetic and Bromide Counterions: Synthesis, Thermal Behavior, Magnetic Performance, and Surface Properties.

Langmuir : the ACS journal of surfaces and colloids·2026

Same author

Effects of interfacial hydrogen bonding and electrostatic interactions on the adsorption and foaming properties in saponin mixtures.

Journal of colloid and interface science·2026

Same author

X‑rays to Probe Compression across Scales in Rigid Polyurethane Foams: Molecular Simulations and Synchrotron Experiments.

ACS omega·2026

Same journal

Tris(vinyl dimethylsilyl) phosphate: Enhancing interface stability in high-voltage Li-ion batteries at elevated temperatures.

Journal of colloid and interface science·2026

Same journal

Electron-donor modulated built-in electric fields in Ni<sub>2</sub>P/MoS<sub>2</sub> Heterostructures for accelerated sodium storage kinetics.

Journal of colloid and interface science·2026

Same journal

Porous flexible structure mediated synergistic boost of built-in electric field and photothermal effect for enhanced photocatalysis.

Journal of colloid and interface science·2026

Same journal

Bi/Bi<sub>2</sub>Ce<sub>2</sub>O<sub>7</sub> heterojunctions for visible-light photocatalytic nitrogen fixation: Synergistic enhancement by localized surface plasmon resonance and oxygen vacancies.

Journal of colloid and interface science·2026

Same journal

Interface engineering of ultrathin nickel metallene on titanium dioxide nanosheets for efficient photocatalytic hydrogen evolution.

Journal of colloid and interface science·2026

Same journal

Magnetic Janus droplets as soft robots.

Journal of colloid and interface science·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 2, 2026

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer

Published on: April 23, 2017

Structural evolution of supported lipid bilayers intercalated with quantum dots.

Magdalena Wlodek¹, Anna Slastanova², Laura J Fox²

¹Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Niezapominajek 8, PL-30239 Krakow, Poland.

Journal of Colloid and Interface Science

|December 7, 2019

Summary

This summary is machine-generated.

Hydrophobic quantum dots (QDs) cause supported lipid bilayers (SLBs) to rearrange over time. Structural changes, including thickness and density shifts, reveal QDs moving within the bilayer, impacting SLB applications.

Keywords:

Bilayer structure Membranes intercalated with quantum dots Nanoparticle-membrane interactions Supported lipid bilayers X-ray reflectivity (XRR)

More Related Videos

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions

Published on: August 3, 2021

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Published on: July 22, 2015

Related Experiment Videos

Last Updated: Jan 2, 2026

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer

Published on: April 23, 2017

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions

Assembly of Cell Mimicking Supported and Suspended Lipid Bilayer Models for the Study of Molecular Interactions

Published on: August 3, 2021

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers

Published on: July 22, 2015

Area of Science:

Materials Science
Biophysics
Nanotechnology

Background:

Supported lipid bilayers (SLBs) are crucial for biomimetic systems.
Incorporating hydrophobic quantum dots (QDs) into SLBs can enhance their functionality.
Understanding the structural dynamics of QD-embedded SLBs is essential for their application.

Purpose of the Study:

To investigate the temporal structural evolution of supported lipid bilayers (SLBs) embedded with hydrophobic quantum dots (QDs).
To elucidate the mechanistic insights into the structural rearrangement of QD-SLBs over time.

Main Methods:

Synchrotron X-ray reflectivity (XRR) was used to monitor structural changes in QD-SLBs over 24 hours.
Atomic force microscopy (AFM) provided complementary characterization of bilayer morphology.
QD-SLBs were formed by rupturing mixed liposomes (POPC/POPE) onto a polyethylene imine (PEI) monolayer.

Main Results:

QD incorporation induced time-dependent structural perturbations in SLBs.
Initially, QD-SLBs showed decreased thickness and increased scattering length density (SLD).
Over time, QD-SLBs progressively thickened, indicating structural rearrangement with QDs migrating to the outer leaflet.

Conclusions:

The study reveals unprecedented mechanistic insights into the structural evolution of QD-SLBs.
QD-induced structural rearrangement is a key factor in QD-SLB dynamics.
Findings are vital for advancing the potential biomedical and biosensing applications of QD-SLBs.