Related Experiment Video

Updated: Jan 2, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.4K

Pediatric Drug Induced Sleep Endoscopy: A Simple Sedation Recipe

Adam C Adler1, Mary F Musso2,3, Deepak K Mehta2,3

  • 1Department of Anesthesiology, Perioperative and Pain Medicine, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.

The Annals of Otology, Rhinology, and Laryngology
|December 7, 2019
PubMed

Insights

A new minimalist sedation approach successfully sedated 15 complex pediatric patients for DISE procedures without airway intervention. This method offers a safe alternative for children with comorbidities undergoing diagnostic sleep endoscopy.

Area of Science:

  • Pediatric Anesthesiology
  • Sleep Medicine
  • Otolaryngology

Background:

  • Diagnostic Sleep Endoscopy (DISE) requires appropriate sedation for accurate assessment.
  • Sedation in complex pediatric patients presents unique challenges due to comorbidities.

Purpose of the Study:

  • To present a minimalist sedation strategy for pediatric DISE procedures.
  • To evaluate the efficacy and safety of this approach in complex pediatric cases.

Main Methods:

  • Literature review to inform an evidence-based sedation algorithm.
  • Algorithm derivation and testing in a cohort of pediatric patients undergoing DISE.
  • Minimalist sedation protocol focused on avoiding airway intervention.

Main Results:

  • Successful sedation without the need for airway intervention in 15 highly complex pediatric patients.
  • The approach was effective across a variety of comorbidities.
  • No adverse events related to sedation or airway management were reported.

Conclusions:

  • A minimalist sedation approach is feasible and effective for pediatric DISE in complex patients.
  • This strategy may reduce the need for advanced airway management during DISE.
  • Further research is warranted to compare outcomes against natural sleep states.
Abstract

Keywords:
adenotonsillectomyinhaled anestheticspediatricssleepsleep endoscopy

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