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Author Spotlight: Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
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Head turning sign.

Mona Ghadiri-Sani1, Andrew J Larner2

  • 1Walton Centre for Neurology and Neurosurgery, Liverpool, UK.

The Journal of the Royal College of Physicians of Edinburgh
|December 7, 2019
PubMed
Summary
This summary is machine-generated.

The head turning sign, noted for over 20 years, is frequently seen in patients with cognitive disorders, particularly Alzheimer's disease. Further research is needed to understand its underlying causes.

Keywords:
Alzheimer’s diseasedementiadiagnosishead turning signmild cognitive impairment

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Area of Science:

  • Neurology
  • Cognitive Science
  • Geriatrics

Background:

  • The head turning sign was first described over two decades ago.
  • Recent empirical studies have begun assessing this sign in large patient cohorts with cognitive disorders.
  • Operational definitions of the sign have varied across studies.

Purpose of the Study:

  • To report on the frequency and context of the head turning sign in patients evaluated for cognitive disorders.
  • To investigate the prevalence of the head turning sign in different cognitive conditions.
  • To highlight the potential clinical utility of the head turning sign.

Main Methods:

  • Analysis of large cohorts of patients undergoing assessment for cognitive disorders.
  • Observation and categorization of the head turning sign.
  • Comparison of sign frequency across different diagnostic groups (Alzheimer's disease, other dementias, mild cognitive impairment).

Main Results:

  • The head turning sign is frequently observed in cognitive clinic patient cohorts.
  • The sign is more prevalent in Alzheimer's disease compared to other dementias.
  • An intermediate frequency of the head turning sign was noted in mild cognitive impairment.

Conclusions:

  • The head turning sign is an easily observable indicator that may suggest the presence of a cognitive disorder.
  • The sign appears to be a relevant clinical observation in the context of cognitive decline.
  • The precise neuropsychological, psychiatric, and neurobiological underpinnings of the head turning sign require further investigation.