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Tramadol Does Not Improve Performance or Impair Motor Function in Trained Cyclists.

Jacob Bejder¹, Andreas Breenfeldt Andersen¹, Thomas Christian Bonne¹

¹Department of Nutrition, Exercise and Sports (NEXS), University of Copenhagen, DENMARK.

Medicine and Science in Sports and Exercise

|December 7, 2019

Summary

A 100 mg dose of Tramadol did not enhance cycling performance or impair cognitive function in highly trained cyclists. Fine motor skills showed a slight improvement with Tramadol.

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Area of Science:

Sports Science
Exercise Physiology
Pharmacology

Background:

Athletes often seek performance-enhancing substances.
Tramadol is an analgesic with potential central nervous system effects.
Its impact on athletic performance and cognitive function requires investigation.

Purpose of the Study:

To determine if oral Tramadol improves cycling time trial performance.
To assess if Tramadol compromises motor-cognitive function in cyclists.

Main Methods:

16 highly trained cyclists participated in a double-blind, placebo-controlled crossover study.
Participants completed a 15-km cycling time trial after a 1-hour preload at 60% peak power.
Motor-cognitive tasks were assessed during the preload phase.

Main Results:

Tramadol did not significantly alter time trial performance or mean power output.
No differences were observed in perceived exertion, pain, or key blood markers.
Heart rate was slightly higher with Tramadol, but motor-cognitive performance was not impaired, with fine motor skills showing improvement.

Conclusions:

A 100 mg dose of Tramadol does not enhance 15-km cycling time trial performance in trained cyclists.
Therapeutic Tramadol does not impair complex motor-cognitive or simple fine motor performances in this population.