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Updated: Jan 2, 2026

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona
Jiaying Zhu1, Yang Liu1, Zijun Liu1
1School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China.
Abstract:
Marine sponge genus Haliclona, one of the most prolific sources of natural products, contains over 600 species but only a small part of them had been classified and chemically investigated. On the basis of extensive literature search, this review firstly summarizes 112 nitrogenous secondary metabolites from classified and unclassified Haliclona sponges as well as from their symbiotic microorganisms. Most of these substances have only been found in Haliclona sponges, and display diverse bioactive properties with potential applications in new drug discovery.
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