Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stages of General Anesthesia01:22

Stages of General Anesthesia

1.4K
Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
1.4K
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

525
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
525
Sedatives and Hypnotics: Overview01:23

Sedatives and Hypnotics: Overview

1.3K
Sedatives are drugs that alleviate anxiety, while hypnotics induce sleep. Both classes of medication suppress neuronal activity, leading to a calming effect for sedatives and facilitating sleep for hypnotics.
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
1.3K
Sedatives and Hypnotics Drugs: Benzodiazepines01:19

Sedatives and Hypnotics Drugs: Benzodiazepines

687
Benzodiazepines have both sedative and hypnotic properties. They include compounds such as diazepam (Valium) and alprazolam (Xanax). Structurally, their cores are similar, consisting of the fusion of a benzene ring and a diazepine ring, but they share a common mechanism of action in the central nervous system (CNS).
Benzodiazepines work by enhancing the effects of the inhibitory neurotransmitter GABA. They bind to the GABAA receptor, increasing its affinity for GABA, which opens chloride...
687
General Anesthesia: Overview01:24

General Anesthesia: Overview

523
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
523
Sedatives and Hypnotics Drugs: Barbiturates01:20

Sedatives and Hypnotics Drugs: Barbiturates

869
Sedatives and hypnotics encompass a drug class that acts on the central nervous system (CNS) to alleviate anxiety, promote relaxation and induce sleep.These drugs function by amplifying the actions of the neurotransmitter γ-aminobutyric acid (GABA), resulting in reduced neuronal activity. Barbiturates, a subset of sedatives and hypnotics first synthesized in the late 1800s, are categorized into ultra-short, short, intermediate, and long-acting groups based on their duration of effect. A...
869

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and Distribution of Maxillary Pathologies Affecting the Maxillary Sinus: A Retrospective Clinical Study.

European journal of dentistry·2026
Same author

Managing post-extubation dysphagia after prolonged intubation: A systematic review of Speech-Language Pathology (SLP) approaches.

American journal of otolaryngology·2026
Same author

Implant-Abutment Interface and Peri-implant Inflammation in One-Piece and Two-Piece Dental Implants: A Narrative Review.

European journal of dentistry·2026
Same author

Effectiveness of PEEK versus zirconia frameworks in fixed dental prostheses: A systematic review and meta-analysis.

The Journal of prosthetic dentistry·2026
Same author

Does heat affect the performance of bioceramic sealers? A systematic review of warm obturation.

Minerva dental and oral science·2026
Same author

Comparative Efficacy of Botulinum Toxin Type A Versus Antihomotoxic Therapy in the Treatment of Bruxism-Related Masticatory Muscle Hyperactivity: A Randomized Clinical Trial Using Electromyographic Measurements.

The Journal of craniofacial surgery·2026

Related Experiment Video

Updated: Jan 2, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.4K

Conscious Sedation in Dentistry.

Luca Fiorillo1

  • 1Department of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Policlinico G. Martino, Via Consolare Valeria, 98100 Me, Italy.

Medicina (Kaunas, Lithuania)
|December 11, 2019
PubMed
Summary

Conscious sedation in dentistry combines local anesthesia with drugs for anxiolysis, improving patient collaboration and reducing surgical time. Tailoring sedation levels ensures patient safety and procedural efficiency for better outcomes.

Keywords:
feargeneral healthinterdisciplinaryoral healthphobiasedationwell-being

More Related Videos

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
14:52

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Published on: January 13, 2018

11.4K
Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

2.2K

Related Experiment Videos

Last Updated: Jan 2, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.4K
Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
14:52

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Published on: January 13, 2018

11.4K
Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
05:39

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia

Published on: May 26, 2023

2.2K

Area of Science:

  • Dentistry
  • Anesthesiology
  • Pharmacology

Background:

  • Local anesthesia is standard for invasive dental procedures, but adjuncts for anxiety are often needed.
  • Patient anxiety and lack of collaboration can prolong dental procedures, impacting post-operative phases.
  • Conscious sedation aims to balance patient comfort, operator needs, and procedural safety.

Discussion:

  • Various conscious sedation methods used in dentistry are reviewed.
  • The manuscript evaluates current techniques for conscious sedation in dental practice.
  • Individualized sedation levels are crucial for optimizing patient care and surgical efficiency.

Key Insights:

  • Conscious sedation can enhance patient cooperation during invasive dental treatments.
  • Adjusting sedation depth is key to balancing patient, operator, and procedural requirements.
  • Effective sedation minimizes interruptions and improves the overall surgical experience.

Outlook:

  • Further research into safer sedative agents for dental patients is warranted.
  • This review serves as a foundation for future advancements in dental sedation.
  • Exploring novel pharmacologic approaches can benefit both patients and dental professionals.