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Effect of Malnutrition on Hearing Loss in Children
Michaela F Close1, Charmee H Mehta, Josh van Swol
1MUSC Otolaryngology, Charleston, South Carolina.
Insights
Children with protein-calorie malnutrition (PCM) have a higher prevalence and severity of hearing loss (HL). Early audiological evaluation and intervention are crucial for malnourished children to improve outcomes.
Area of Science:
- Pediatrics
- Audiology
- Nutritional Science
Background:
- Protein-calorie malnutrition (PCM) is a significant health concern in children.
- Hearing loss (HL) can have profound impacts on a child's development.
- The relationship between PCM and HL requires further characterization.
Purpose of the Study:
- To investigate the association between protein-calorie malnutrition (PCM) and hearing loss (HL) in pediatric populations.
- To determine the prevalence, type, severity, and progression of hearing loss in children with PCM.
Main Methods:
- Retrospective review of children's audiological and genetic database.
- Inclusion criteria: diagnosis of PCM, marasmus, or kwashiorkor.
- Outcome measures: prevalence, type, severity (PTA), and progression of HL.
Main Results:
- Children with PCM showed a higher prevalence of HL (57.8%) compared to those without PCM (45.5%).
- Severely malnourished children had increased odds of moderate-profound, high-frequency, and sensorineural/mixed HL.
- Malnourished children exhibited worse initial and final hearing thresholds and less improvement in HL.
Conclusions:
- Children with PCM are at higher risk for audiological complications, including significant hearing loss.
- Early audiological evaluation and timely intervention are recommended for malnourished children.
- Clinical practice should prioritize nutritional support and audiological screening in this vulnerable population.
Objective:
To characterize the relation between protein-calorie malnutrition (PCM) and hearing loss (HL) in children.
Study Design:
Retrospective review.
Setting:
Tertiary referral hospital.
Patients:
Children in the Audiological and Genetic Database with a diagnosis of protein-calorie malnutrition, marasmus, and/or kwashiorkor.
Interventions:
None.
Main Outcome Measures:
Prevalence, type, severity (4-tone pure-tone average, PTA), and progression of HL.
Results:
Of 770 children with PCM, 57.8% had HL, compared to 45.5% of children without PCM (p < 0.001). Severely malnourished children had significantly higher odds of moderate-profound HL (aOR 2.27, 95% CI 1.47-3.43), high-frequency HL (aOR 1.82, 95% CI 1.21-2.75), and sensorineural or mixed HL (aOR 1.60, 95% CI 1.05-2.41) compared to children without PCM. Severely malnourished children had significantly worse initial (35.0 dB vs 25.0 dB, p < 0.001), and final median PTA (31.3 dB vs 20.0 dB, p < 0.001) compared to children without PCM. Additionally, HL in children who were moderately and severely malnourished was significantly less likely to improve (aOR 0.47, 95% CI 0.25-0.82 and aOR 0.4, 95% CI 0.2-0.9) when compared to those without PCM.
Conclusions:
Given the greater prevalence and severity of hearing loss, children with PCM should be considered an at-risk group for poor audiological outcomes, and clinical practice should focus on early treatment and intervention for malnourished children. Routine audiological evaluation should be considered in this population.
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