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Two cases of meningitis associated with ocrelizumab therapy

Michael Theriault1, Andrew J Solomon1

  • 1Larner College of Medicine at The University of Vermont, Burlington, VT, United States.

Multiple Sclerosis and Related Disorders
|December 11, 2019
PubMed

Insights

Ocrelizumab, a multiple sclerosis (MS) treatment, may rarely cause meningitis. This case report details two instances of meningitis developing within one year of starting ocrelizumab therapy for MS.

Area of Science:

  • Immunology
  • Neurology
  • Pharmacology

Background:

  • Ocrelizumab is a targeted immunotherapy for multiple sclerosis (MS).
  • It is an anti-CD20 monoclonal antibody used for relapsing-remitting MS (RRMS) and primary progressive MS (PPMS).
  • Its efficacy, dosing, and safety profile have led to increased use in MS management.

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