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Alternative splicing in aging and longevity

Malini Bhadra1, Porsha Howell1, Sneha Dutta1

  • 1Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.

Human Genetics
|December 14, 2019
PubMed
Summary

RNA splicing, a key regulator of gene expression, is increasingly recognized as a hallmark of aging. Dysfunctional splicing contributes to aging, while interventions targeting splicing factors may extend lifespan.

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