Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Lysozyme activity of pneumococci].

O V Bukharin, L I Prianishnikova, B Ia Usviatsov

    Antibiotiki
    |December 1, 1978
    PubMed
    Summary

    Lysozyme activity was found in 41.2% of pneumococcal strains, particularly in those from patients. These lysozyme-active strains showed increased antibiotic resistance and virulence in mice.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Environmental Determination of Indigenous Bifidobacteria of the Human Intestine.

    Herald of the Russian Academy of Sciences·2022
    Same author

    Diagnostic cytokine marker of male infertility - interleukin 4.

    Klinicheskaia laboratornaia diagnostika·2022
    Same author

    [Characterization of the microbiota and cytokine profile of sperm plasma in men with chronic bacterial prostatitis].

    Urologiia (Moscow, Russia : 1999)·2020
    Same author

    [GUT MICROSYMBIOCENOSIS IN CHILDREN WITH REACTIVE ARTHRITIS].

    Zhurnal mikrobiologii, epidemiologii i immunobiologii·2019
    Same author

    [INTERMICROBIAL <<SELF-NON-SELF>> DISCRIMINATION IN <<DOMINANT-ASSOCIANT>> PAIR OF PROBIOTIC STRAINS OF ESCHERICHIA COLI M-17 AND E.COLI LEGM-18].

    Zhurnal mikrobiologii, epidemiologii i immunobiologii·2019
    Same author

    [METABOLIC PROFILE OF BIFIDOFLORA UNDER DIFFERENT MICROECOLOGICAL CONDITIONS OF THE COLON BIOTOPE IN HUMAN].

    Zhurnal mikrobiologii, epidemiologii i immunobiologii·2019

    Area of Science:

    • Microbiology
    • Bacteriology
    • Immunology

    Background:

    • * Streptococcus pneumoniae (pneumococcus) is a major human pathogen.
    • * Lysozyme is a key component of the innate immune system.
    • * Understanding pneumococcal traits like lysozyme activity is crucial for infection control.

    Purpose of the Study:

    • * To investigate the prevalence of lysozyme activity in pneumococcal strains.
    • * To determine the correlation between lysozyme activity and other bacterial characteristics.
    • * To assess the relationship between lysozyme activity and pneumococcal virulence.

    Main Methods:

    • * Culturing and examination of 329 pneumococcal strains.
    • * Assessment of lysozyme activity using specific methods.
    • * Evaluation of antibiotic resistance, capsule formation, and phagocytosis resistance.

    Main Results:

    • * 41.2% of pneumococcal cultures exhibited lysozyme activity.
    • * Lysozyme activity frequency varied based on the detection method.
    • * Strains with lysozyme activity were more common in patients than healthy individuals.
    • * Lysozyme-active strains showed higher antibiotic resistance.
    • * Lysozyme activity correlated with increased virulence in mice, enhanced capsule formation, and greater resistance to phagocytosis.

    Conclusions:

    • * Lysozyme activity is a significant feature in a subset of pneumococcal strains.
    • * This activity is associated with traits that contribute to pneumococcal pathogenicity.
    • * The findings suggest lysozyme activity may be a marker for more virulent and resistant pneumococcal isolates.

    Related Experiment Videos