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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

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Uveal Melanoma.

Ulrich Pfeffer1

  • 1IRCCS Ospedale Policlinico San Martino, 15132 Genova, Italy.

Cancers
|December 15, 2019
PubMed
Summary
This summary is machine-generated.

Uveal melanoma (UM) is a well-studied eye cancer. This research explores its genetic landscape to identify new therapeutic targets.

Area of Science:

  • Ophthalmology
  • Oncology
  • Genetics

Background:

  • Uveal melanoma (UM) is the most common primary intraocular malignancy in adults.

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  • Despite its rarity, UM exhibits significant metastatic potential and poor prognosis.
  • Understanding the molecular drivers of UM is crucial for developing effective treatments.