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Primary intracranial plasma-cell granuloma. Case report
D M Cannella1, A P Prezyna, J P Kapp
1Department of Neurosurgery, State University of New York, Buffalo.
Journal of Neurosurgery
|November 1, 1988
Summary
This study details a rare intracranial plasma-cell granuloma in a teenage girl, presenting with vision loss. The tumor mimicked a meningioma, requiring radiation therapy after initial surgical and steroid treatment failure.
Area of Science:
- Neuropathology
- Neurosurgery
- Oncology
Background:
- Primary intracranial plasma-cell granuloma is an exceptionally rare tumor.
- Distinguishing it from more common neoplasms like meningioma is critical for appropriate management.
Observation:
- A 16-year-old female presented with significant vision loss.
- The intracranial mass exhibited features suggestive of a meningioma on imaging and during surgical exploration.
Findings:
- Subtotal surgical excision and subsequent steroid therapy were ineffective.
- Radiation therapy was administered due to the lack of response to initial treatments.
- The case highlights the challenges in diagnosing and managing this rare entity.
Implications:
- This case underscores the importance of considering rare diagnoses in the differential for intracranial tumors.
- Effective treatment strategies for intracranial plasma-cell granuloma may involve a multimodal approach.
- Further research is needed to elucidate optimal therapeutic protocols for this condition.
