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Updated: Jan 1, 2026

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis
Published on: May 10, 2022
Eating Disorders and Gastrointestinal Diseases
Antonella Santonicola1, Mario Gagliardi1, Michele Pier Luca Guarino2
1Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, 84084 Salerno, Italy.
Eating disorders (ED) are linked to gastrointestinal (GI) issues, with intestinal microbiota potentially playing a key role. Investigating GI symptoms in ED patients and screening for ED in those with unexplained GI complaints is crucial for effective treatment.
Area of Science:
- Gastroenterology
- Psychiatry
- Microbiology
Background:
- Eating disorders (ED) like anorexia nervosa, bulimia nervosa, and binge eating disorder are frequently linked with psychiatric and somatic conditions.
- Patients with ED commonly experience both upper and lower gastrointestinal (GI) symptoms, suggesting a significant GI tract involvement.
Purpose of the Study:
- To review the association between eating disorders and gastrointestinal diseases.
- To explore potential underlying factors, including the role of intestinal microbiota, in the pathogenesis of these conditions.
Main Methods:
- Analysis of existing evidence on GI alterations in patients with ED.
- Review of recent clinical studies on the role of intestinal microbiota in ED development and progression.
Main Results:
- Evidence suggests alterations throughout the GI tract in ED patients, impacting food intake and regulation.
- The role of intestinal microbiota in ED pathogenesis is increasingly recognized, suggesting potential therapeutic modulation.
- The origin of GI disorders in ED (inherent vs. malnutrition-induced) remains under investigation.
Conclusions:
- GI disorders warrant investigation in all patients diagnosed with ED.
- Screening for ED should be considered in individuals presenting with unexplained GI complaints to improve therapeutic outcomes.
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