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Updated: Jan 1, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Neutral and cationic enantiopure group 13 iminophosphonamide complexes
Bhupendra Goswami1, Ravi Yadav, Christoph Schoo
1Institut für Anorganische Chemie, Karlsruher Institut für Technologie (KIT), Engesserstr. 15, Geb. 30.45, 76131 Karlsruhe, Germany. roesky@kit.edu.
Abstract:
Synthesis and reactivity of enantiopure iminophosphonamide ligand L-H (L = [Ph2P{N(R)CH(CH3)Ph}2]) with group 13 metal compounds has been investigated. The reaction of L-H with LiAlH4 afforded the aluminium monohydride complex [L2AlH]. The monochloride complexes [L2MCl] (M = Al, Ga) were accessed by reacting corresponding MCl3 (M = Al, Ga) with L-Li. Furthermore, the tetracoordinated aluminium cation [L2Al]+[GaCl4]- and gallium cation [L2Ga]+[AlCl4]- were obtained by chloride abstraction from [L2MCl] (M = Al, Ga), respectively. The title complexes represent the first examples of enantiopure group 13 metal complexes coordinated by chiral iminophosphonamides. All complexes have been characterized by single crystal X-ray diffraction, multinuclear NMR, EA and IR studies.
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