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Labelling accuracy in low nicotine e-cigarette liquids from a sampling of US manufacturers
Remonica Jackson1, Mariah Huskey1, Stacy Brown1
1Department of Pharmaceutical Sciences, Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, USA.
Objectives:
To assess labelling accuracy for low nicotine concentration e-cigarette liquids.
Methods:
Nicotine concentration in twelve e-liquids, available in 3 and 6 mg/ml strengths, was assayed (5 replicates each) using liquid chromatography-tandem mass spectrometry.
Key Findings:
Average nominal concentrations of nicotine were lower than reported in 23/24 products tested, with 2/12 products labelled 3 mg/ml, and 3/12 of the 6 mg/ml products showing statistically significant differences from controls.
Conclusions:
Despite the emergence of a global regulatory environment for e-cigarettes, inaccuracies still exist in nicotine concentration labelling, which may affect user habits and reliability of products used in smoking cessation.
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