Related Experiment Video
Updated: Jan 1, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Pre and Post-Operative Ph-Metry in Videolaparoscopic Surgery for Gastro Oesophageal Reflux Disease
A Garzi1, G Ardimento2, U Ferrentino2
1Division of Pediatric M.I.S. and Robotic Surgery University of Salerno, Italy.
Insights
Gastro-oesophageal reflux is common in infants and can cause serious complications. Minimally invasive surgery and pH-metry offer effective diagnosis and treatment for pediatric reflux disease.
Area of Science:
- Pediatric Gastroenterology
- Surgical Innovation
Background:
- Gastro-oesophageal reflux (GER) is common in children, particularly infants, and can be physiological.
- Immature anatomical structures in infants increase the risk of GER disease, leading to symptoms and potential complications like oesophagitis and stenosis.
- GER disease diagnosis involves morphological and functional assessments, with pH-metry enabling personalized therapeutic strategies.
Purpose of the Study:
- To evaluate the effectiveness of minimally invasive surgical approaches for pediatric reflux disease.
- To assess the role of pH-metry in planning and monitoring treatment outcomes in children with GER disease.
Main Methods:
- Retrospective analysis of 18 children with reflux disease treated with videolaparoscopic Nissen (14) or Toupet (4) fundoplication.
- Pre- and post-operative pH-metry to evaluate esophageal acid exposure and clearance.
- Utilized pH-metry for therapeutic strategy planning and follow-up monitoring, especially in neurologically impaired children.
Main Results:
- Videolaparoscopic surgery significantly improved the functioning of the gastro-oesophageal junction.
- Post-operative pH-metry demonstrated reduced distal esophageal acid exposure and improved esophageal clearance.
- pH-metry proved valuable for therapeutic planning and avoiding invasive tests in follow-up evaluations.
Conclusions:
- Minimally invasive surgery, including Nissen and Toupet fundoplication, is effective for treating pediatric reflux disease.
- pH-metry is an invaluable tool for diagnosing, planning treatment, and monitoring outcomes in children with GER disease.
- This approach is particularly beneficial for managing GER in children with severe neurological impairment.
Abstract:
Gastro-oesophageal reflux is common in children, especially in the first year of life, and it may be regarded as physiological. Good functioning of the lower oesophageal sphincter depends largely on the anatomical relationships between oesophagus, stomach and diaphragm hiatus. Relative immaturity of these structures in newborn babies and young children is a risk factor in reflux disease, which may result in a wide variety of typical and/or atypical symptoms and, sometimes, serious complications such as oesophagitis and stenosis. Reflux disease may be diagnosed and studied, basing on morphological and functional aspects and, since the advent of pH-metry, it is possible to personalise the therapeutic approach to children with reflux. Surgical treatment of reflux disease in children has recently been improved due to a mini-invasive surgical approach. Absolute indications are recurrent pneumonia, intractable pain due to oesophagitis and retarded growth, often in association with neurological impairment. In the last three years, 18 children with reflux disease underwent videolaparoscopic surgery in our department, 14 by the Nissen and 4 by the Toupet technique. Post-operative pH-metry always showed a reduction in exposure of the distal oesophagus to acid (integral of H+) and an improvement in oesophageal clearance (short refluxes percentage) indicative of good functioning of the gastro-oesophageal junction. PH-metry proved to be an invaluable technique for planning therapeutic strategy. In follow-up evaluations, it enabled us to monitor functioning of the gastro-oesophageal junction and to avoid other more difficult and invasive tests in patients with severe neurological impairment.
Related Concept Videos
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:
Esophageal Varices-I: Introduction
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...

