Bimetallic nickel-ferrite nanorod particles: greener synthesis using rosemary and its biomedical efficiency

Nickel-ferrite (NiFe₂O₄) nanorods particles (NRP) was biosynthesised for the first time by the Rosemary Extract. The NRP was fully characterised, including the type, nanostructure and physicochemical properties of using XRD, HRTEM, FeSEM, XPS, FTIR and VSM. TEM confirmed rod-shaped nano-sized particles with average sizes ranging from 10 nm to 28 nm. The EDAX Analysis showed the presence of iron, nickel, oxygen, and carbon. XRD analysis confirmed the synthesis of NiFe₂O₄ crystals. XPS curves showed photoelectron for iron, oxygen and nickel. EDS showed the atomic, weight percentages ratios of Ni(12%): Fe(24%) and: O(48) are close to the theoretical value (Ni: Fe:O = 1:2:4), of bimetallic magnetic NiFe₂O₄ NRP. NiFe₂O₄ NRP had cytotoxicity effect on MCF-7 cells survival which suggests that NiFe₂O₄ NRP can be used as a new class of anticancer agent in design novel cancer therapy research.