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Related Experiment Video

Updated: Jan 1, 2026

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One Step Away from Technology but One Step Towards Domain Experts-MDRBridge: A Template-Based ISO 11179-Compliant

Ann-Kristin Kock-Schoppenhauer1, B Kroll1, M Lambarki2

  • 1IT Center for Clinical Research, University of Lübeck, Germany.

Methods of Information in Medicine
|December 20, 2019
PubMed
Summary
This summary is machine-generated.

Metadata repositories (MDRs) are crucial for secondary data use, but metadata collection is challenging. MDRBridge, using MDRSheet, simplifies metadata capture and processing, improving domain expert involvement and acceptance.

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Area of Science:

  • Data management
  • Health informatics
  • Metadata standards

Background:

  • Secondary use of medical data requires shared understanding via metadata in repositories (MDRs).
  • Local metadata work is time-consuming and challenging for domain experts.

Purpose of the Study:

  • To support identification, collection, and structured provision of metadata for consolidation.
  • To enhance user acceptance in metadata management processes.

Main Methods:

  • Proposed MDRBridge software pipeline with MDRSheet, an ISO 11179-3 compliant template.
  • Supported manual entry and automatic extraction of metadata.
  • Developed ISO 11179 to Clinical Data Interchange Standards Consortium (CDISC) Operational Data Model (ODM) mapping for MDR export.

Main Results:

  • MDRSheet within MDRBridge delivers metadata in CDISC ODM format for MDRs.
  • Enabled interactive unification of datasets, import of standard datasets, and automatic data element extraction.
  • Significantly improved clinical domain expert involvement with minimal workflow changes.

Conclusions:

  • High user acceptance achieved by adapting to clinical domain experts' workflows.
  • The process transforms data elements to ISO 11179-3 format.
  • MDRSheet serves as an intermediate format for easy viewing and editing by domain experts.