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[A Case of Aortic Graft Infection Due to Listeria monocytogenes Detected by Microarray-Based, Multiplexed, Automated
Mai Kodama1, Masaki Nakanishi1, Naohisa Fujita1
1Department of Infection Control and Laboratory Medicine, Kyoto Pregectual University of Medicine, 465 Kajii-cho, Kamigyou-ku, Kyoto 162-8566, Japan.
Abstract:
A 80-year-old man was transferred to our hospital for hemoptysis caused by erosion(perforation) of thoracic aortic stent graft infection into the airway. Blood cultures on admission detected Gram-positive rods, and a microarray-based, multiplexed, automated molecular diagnosis instrument (Verigene® system) identified Listeria spp. Although Listeria monocytogenes is rare organism of stent graft infection, we were able to start appropriate antibiotic therapy on the second hospital day due to rapid identification of bacteria. Verigene® system is considered to be useful in severe infectious diseases including stent graft infections, even if the causative organism is rare.
Insights
Rapid identification of rare Listeria stent graft infection using the Verigene® system enabled prompt antibiotic therapy. This automated molecular diagnosis instrument proved valuable for severe infections, even with unusual pathogens.
Area of Science:
- Infectious Diseases
- Medical Microbiology
- Cardiovascular Surgery
Background:
- Thoracic aortic stent graft infections are severe complications, potentially leading to life-threatening conditions like hemoptysis.
- Erosion of infected stent grafts into adjacent airways presents a significant diagnostic and therapeutic challenge.
- Timely and accurate identification of causative pathogens is crucial for effective treatment of stent graft infections.
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