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Updated: Jan 1, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Is there a role for arcing techniques in proton therapy?
Alejandro Carabe-Fernandez1, Alejandro Bertolet-Reina1, Ilias Karagounis1
1Department of Radiation Oncology, University of Pennsylvania, Philadelphia, USA.
Abstract:
Proton arc therapy (PAT) has been proposed as a possible evolution for proton therapy. This commentary uses dosimetric and cancer risk evaluations from earlier studies to compare PAT with intensity modulated proton therapy. It is concluded that, although PAT may not produce better physical dose distributions than intensity modulated proton therapy, the radiobiological considerations associated with particular PAT techniques could offer the possibility of an increased therapeutic index.

