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Lethal infective endocarditis due to Streptococcus agalactiae in a man with a history of alcohol abuse: A case report
Myriam D'Angelo1, Ilaria Boretti1, Salvina Quattrocchi1
1Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Centro Neurolesi "Bonino Pulejo", Messina.
Insights
A rare case of recurrent infective endocarditis caused by Streptococcus agalactiae in a healthy man led to severe complications. This infection has high mortality, especially with neurological issues and heart failure.
Area of Science:
- Cardiology
- Infectious Diseases
- Neurology
Background:
- Infective endocarditis (IE) is an infection affecting the heart's inner lining, often involving heart valves.
- Streptococcus agalactiae is an uncommon cause of IE, particularly in individuals without pre-existing heart conditions.
Observation:
- A 53-year-old man with a history of alcohol abuse presented with fever, atrial fibrillation, and pulmonary infection.
- The patient developed recurrent severe endocarditis with both ischemic and hemorrhagic neurological complications and heart failure.
Findings:
- The case highlights the rarity of IE caused by Streptococcus agalactiae in an otherwise healthy individual.
- Neurological complications, heart failure, and recurrent IE, especially with valve prosthesis, are associated with high mortality.
Implications:
- This case underscores the critical need for prompt diagnosis and management of IE, even with unusual pathogens.
- Early recognition and treatment are crucial for improving outcomes in patients with IE and associated neurological and cardiac complications.
Rational:
Infective endocarditis (IE) is defined as an infection of the endocardial surface of the heart, which may include one or more heart valves, the mural endocardium.
Patient Concerns:
A 53-years-old man with a history of alcohol abuse was admitted in hospital for fever, paroxysmal atrial fibrillation cardioverted by Amiodarone and pulmonary infection.
Diagnosis:
A case of recurrent severe endocarditis, with neurological complications both ischemic and hemorrhagic and heart failure caused by Streptococcus agalactiae in healthy man we reported.
Interventions:
Surgery was performed 2 weeks after admission.
Outcomes:
The onset of intracranial hemorrhage delayed second cardiac surgery and the patient died because of end-stage heart failure.
Conclusions:
Infective endocarditis caused by S. agalactiae is very rare, particularly in patients without underlying structural heart disease. This study showed that IE due to S. Agalactiae is a disease with high mortality when associated with neurological complication, heart failure but especially when it is recurrent and hits valve prosthesis.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Rheumatic Heart Disease I: Introduction
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.

