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Updated: Jan 1, 2026

Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
Impact of gut microbiota on neurogenesis and neurological diseases during infancy
Tomás Cerdó1, Estefanía Diéguez2, Cristina Campoy3
1Department of Paediatrics, School of Medicine, University of Granada, Avda. De la Investigación 11, 18016 Granada, Spain; EURISTIKOS Excellence Centre for Paediatric Research, Biomedical Research Centre, University of Granada, 18016 Granada, Spain; BioHealth Research Institute (Ibs), Granada, Health Sciences Technological Park, 18016 Granada, Spain; Neurosciences Institute, Biomedical Research Centre, University of Granada, Spain.
Abstract:
The first years of life constitute a crucial period for neurodevelopment and a window of opportunity to develop new strategies to prevent neurological and mental diseases. Different studies have shown the influence of gut bacteria in neurogenesis and a functional relationship between gut microbiota and the brain, known as 'gut-brain axis', in which the intestinal microbiota is proposed to play a key role in neurophysiological processes. It has been observed that certain microbiome metabolites could be related to the development of neurological disorders through mechanisms still unknown. Then, more studies are needed to broaden the knowledge regarding the relationship between the Central Nervous System and the gastrointestinal tract, which could help to develop new preventive and treatment protocols.
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