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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Updated: Jan 1, 2026

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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Ocular changes in patients with psoriasis.

Zdravka Demerdjieva1, Iskra Mazhdrakova2, Nikolai Tsankov1

  • 1Department of Dermatology, Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria.

Clinics in Dermatology
|December 23, 2019
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Summary
This summary is machine-generated.

Psoriasis, a systemic disease, can affect the eyes, causing various ophthalmic complications like uveitis and cataracts. Early recognition of these eye issues is crucial for effective management.

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Area of Science:

  • Ophthalmology
  • Dermatology
  • Systemic Inflammatory Diseases

Background:

  • Psoriasis is a chronic systemic inflammatory disease.
  • Ocular manifestations of psoriasis are often overlooked by healthcare professionals.
  • Psoriatic eye disease can impact various ocular structures.

Purpose of the Study:

  • To highlight the spectrum of ophthalmic complications associated with psoriasis.
  • To emphasize the importance of recognizing ocular involvement in psoriatic patients.
  • To discuss the pathogenic mechanisms underlying psoriatic eye disease.

Main Methods:

  • Literature review of reported ocular complications in psoriasis patients.
  • Analysis of pathogenic mechanisms including direct plaque involvement, immune-mediated inflammation, and treatment side effects.
  • Synthesis of clinical findings on common eye conditions in psoriasis.

Main Results:

  • Common ocular complications include blepharitis, conjunctivitis, keratitis, iridocyclitis, UV-induced cataracts, uveitis, and birdshot chorioretinitis.
  • Ophthalmic involvement can affect nearly all parts of the eye.
  • Multiple pathogenic pathways contribute to eye disease in psoriasis.

Conclusions:

  • Ocular complications are a significant concern in psoriasis management.
  • Dermatologists and ophthalmologists must be aware of potential eye involvement.
  • Understanding the pathogenesis is key to managing psoriatic eye disease.